Phenylpropanoids and polyketides
Medchemexpress LLC 5-Hydroxyflavone | 491-78-1 | 99.8% | 238.24 | 100 MG
5-Hydroxyflavone | 491-78-1 | 99.8% | 238.24 | 100 MG
Medchemexpress LLC 4H-1-benzopyran-4-one, 2-(4-hydroxyphenyl)- | 4143-63-9 | MFCD00017687 | 97.0% | 238.24 g/mol | C15H10O3 | 25 MG
4′-Hydroxyflavone is a flavone-class small molecule for biochemical and pharmacological research. It is a reported aldose reductase inhibitor (IC50 = 12 μM) and is supplied as a purified solid suitable for in vitro assays, target validation, and screening studies. Typical analytical data include CAS 4143-63-9, molecular formula C15H10O3, and molecular weight 238.24 g/mol.
- Reported aldose reductase inhibitor (IC50 = 12 μM).
- High purity solid (97.0%).
- Characterized by CAS 4143-63-9 and molecular formula C15H10O3.
- Suitable for biochemical assays, target validation, and screening.
- Available in small research pack sizes for laboratory use.
Medchemexpress LLC 4'-hydroxyflavone | 4143-63-9 | MFCD00017687 | 97.0% | 238.24 g/mol | C15H10O3 | 5 MG
4'-Hydroxyflavone is a small-molecule flavone provided for research use. It has the chemical formula C15H10O3, a molecular weight of 238.24 g/mol, and is reported to inhibit aldose reductase (IC50 = 12 μM). The material is intended as a reference reagent for biochemical, pharmacological, and enzymology studies.
- High purity (97.0%) suitable for analytical and biological assays.
- Reported aldose reductase inhibitor (IC50 = 12 μM) for target validation studies.
- Well-characterized chemical identity and molecular properties.
- Available in small pack sizes appropriate for research applications.
- Suitable for biochemical assays, enzymology, and screening workflows.
Selleck Chemical LLC 6-Hydroxyflavone (6-HF) S3634-25mg
6-Hydroxyflavone a naturally occurring flavonoid binds to GABAA receptors with moderate affinity and acts as a partial agonist of GABAA receptors
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | 1 ML
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* that exhibits anti-inflammatory activity. It protects renal cells from nicotine-associated cytotoxicity through the ERK/Nrf2/HO-1 pathway. This compound inhibits PKM2, COX-2, and 5-LOX, and is orally active.
- Inhibits nicotine-induced cytotoxicity and reduces ROS production in renal cells
- Inhibits EV71 3C protease, blocking viral replication
- Decreases malondialdehyde and ROS levels, increases SOD and GSH levels in HepG2 cells
- Inhibits inflammatory cytokines and reduces myocardial injury markers in rat models
- Ameliorates Paclitaxel or Vinorelbine-induced neuropathic pain in mice models
- Reduces fat accumulation, improves hepatic steatosis and oxidative stress in NAFLD models
Selleck Chemical LLC Troxerutin S2369-1g
Troxerutin a natural bioflavonoid isolated from Sophora japonica has been reported to have many benefits and medicinal properties Troxerutin also known as vitamin P4 is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation
Medchemexpress LLC 4H-1-benzopyran-4-one, 2-(4-hydroxyphenyl)- | 4143-63-9 | MFCD00017687 | 97.0% | 238.24 | C15H10O3 | 50 MG
4′-Hydroxyflavone is a flavone derivative supplied as a research-grade chemical for biochemical and pharmacological studies. It inhibits the enzyme aldose reductase (reported IC50 12 μM) and is provided with batch-specific documentation for laboratory use only.
- Inhibits aldose reductase (IC50 = 12 μM).
- High purity: 97.0%.
- Molecular formula C15H10O3; molecular weight 238.24.
- Supplied as a small-molecule reagent for in vitro studies.
- Datasheet and certificate of analysis available.
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | MFCD00006835 | 50 MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* that exhibits anti-inflammatory activity. It protects renal cells from nicotine-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This orally active compound also inhibits PKM2, COX-2, and 5-LOX, and has demonstrated antioxidant activity and efficacy in various animal models.
- Isolated from *Clerodendrum phlomidis*
- Exhibits anti-inflammatory activity
- Protects renal cells from nicotine-associated cytotoxicity
- Inhibits PKM2, COX-2, and 5-LOX
- Orally active
- Reduces malondialdehyde (MDA) and reactive oxygen species (ROS) levels
- Increases superoxide dismutase (SOD) and glutathione (GSH) levels
- Ameliorates ischemia/reperfusion injury
- Improves high-fat diet-induced non-alcoholic fatty liver disease and obesity
- Purity of 99.89%
- Appearance is a white to off-white solid
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | 10 MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* with anti-inflammatory activity. It protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This compound inhibits PKM2 with an IC50 of 2.12 μM and also inhibits COX-2 and 5-LOX with IC50s of 27 μg/mL and 33 μg/mL, respectively. 7-Hydroxyflavone is orally active.
- Isolated from *Clerodendrum phlomidis*.
- Exhibits anti-inflammatory activity.
- Protects renal cells from nicotine-associated cytotoxicity.
- Inhibits PKM2, COX-2, and 5-LOX.
- Orally active.
- Inhibits EV71 3C protease and viral replication.
- Antioxidant properties: decreases MDA and ROS, increases SOD and GSH.
- Ameliorates ischemia/reperfusion injury and neuropathic pain.
- Improves hepatic steatosis and regulates blood glucose metabolism in NAFLD models.